Searchable abstracts of presentations at key conferences in endocrinology

ea0011p235 | Cytokines and growth factors | ECE2006

IGF II protein expression in breast cancer. Relationship with the most important predictive parameters in breast malignancy

Giustarini EG , Pinchera AP , Campani DC , Fierabracci PF , Cullen KC , Giani CG

Recent in situ hybridization data showed high content of IGF-II mRNA in the stroma of breast cancer. The aim of this study was to examine the expression of IGF-II protein and its relationship with several prognostic parameters in 75 ductal infiltrating carcinoma (DIC) of the breast.The tissue sections were evaluated for IGF II protein, proliferating activity, ER, PR, p53, P21 oncogene expression using immunohistochemical procedures. The amoumt of ...